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Title:      ENHANCING PERSONALIZED DIABETES TREATMENT WITH LARGE LANGUAGE MODELS AND CHAIN-OF-THOUGHT REASONING
Author(s):      Qi Sun, Xuekuan Fu and Chenyang Zhou
ISBN:      978-989-8704-61-0
Editors:      Demetrios G. Sampson, Dirk Ifenthaler and Pedro IsaĆ­as
Year:      2024
Edition:      Single
Keywords:      Large Language Model, Chain-of-Thought, Diabetes Treatment, Data Augment
Type:      Short
First Page:      359
Last Page:      364
Language:      English
Cover:      cover          
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Paper Abstract:      Diabetic patients often struggle to determine the appropriate dosage of short-acting insulin to effectively manage their blood glucose levels. Miscalculating the insulin dose can lead to serious complications, such as hypoglycemia or hyperglycemia. In this paper, we propose a novel approach for personalized insulin treatment using large language models (LLMs), dubbed L4DT (Large Language Models for Diabetes Treatment). This method can be divided into two phases. The first phase involves applying chain-of-thought reasoning for data augmentation, simulating so that L4DT could learn the step-by-step thought processes that human experts would use to determine optimal insulin dosages. The second phase focuses on training the LLM to obtain personalized insulin dosage recommendations. Our evaluation of the L4DT demonstrates its expertise in insulin dosage prediction. On the MIMIC-IV dataset, the L4DT model achieves a mean squared error of 4.55 and a mean absolute error of 2.01, outperforming existing approaches. This study not only enhances the application of exploratory learning approaches in complex medical domains but also assesses the impact of exploratory technologies like LLMs on diabetes treatment. The integration of technology and expertise in this model offers a reliable reference for clinicians and a platform for continuous learning and expertise development in the field of diabetes management.
   

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